Richard Ruan

Alexion-AstraZeneca

Hi! I'm currently a Senior Associate Scientist at AstraZeneca, and I work on developing gene therapies for cardiovascular disease. I was formerly a Research Associate at the Broad Institute of MIT and Harvard, working on identifying high-potential therapeutic targets with iPSC-dervied cardiomyocytes.

I graduated from the University of California, Berkeley with my B.S. in Bioengineering and a thesis on a common feature of Dengue and SARS-CoV-2 pathogeneses. I'm passionate about vascular biology, regenerative medicine, medical resource allocation, and good design.

Aside from being a lab workaholic, I enjoy origami (modular and tesselations), writing overly dramatic restaurant reviews on Yelp, practicing Studio Ghibli covers on the piano, and drinking several liters of coffee every day.

ChatGPT and Neurosurgical Education: A Crossroads of Innovation and Opportunity
Journal of Clinical Neuroscience - September 2024
Paper

Awake Craniotomy in Africa: A Scoping Review of Literature and Proposed Solutions to Tackle Challenges
Neurosurgery - March 2023
Paper

SARS-CoV-2 Spike Triggers Barrier Dysfunction and Vascular Leak via Integrins and TGF-β signaling
Nature Communications - December 2022
Paper

Secretion of Leukotrienes by Senescent Lung Fibroblasts Promotes Pulmonary Fibrosis
JCI Insight - November 2019
Paper

Enhancing Quality Control Measures in Upscaled Production of iPSC-Derived Cardiomyocytes for Cardiovascular Research and Therapeutic Development
Massachusetts General Hospital Cardiovascular Research Center Retreat - October 2023

Deep Brain Stimulation in Aggression
Cal Undergraduate Bioengineering Symposium - April 2023

Optimization of an iPSC-based Platform for Large-scale Cardiomyocyte Production
Broad Retreat - December 2022

Using a Murine Model to Study DENV NS1 and SARS-CoV-2 Spike-mediated Vascular Leak
UCSF Bay Area Microbial Pathogenesis Symposium - March 2022

Identifying Host Factors Critical for Viral Toxin-Mediated Vascular Leak
UC Berkeley Haas Scholars Symposium - January 2022

Supporting Medication Plan Adherence in DeLIVER Care Van Hepatitis C Patients
CHORI SSRP Symposium - August 2020

Alexion-AstraZeneca (Cardiovascular Disease)
Senior Associate Scientist | April 2024 - Present

Ellinor Lab - Broad Institute of MIT and Harvard (Cardiovascular Disease)
Collaboration with Bayer and Novo Nordisk
Research Associate 1 | June 2022 - April 2024
Lab Site

Neuro International Collaboration (Neurosurgery)
Team Lead | October 2021 - Present
Website

Harris Lab - UC Berkeley (Infectious Disease)
Haas Scholar | September 2020 - May 2022
Lab Site Haas Scholars SARS-CoV-2 Spike

Children's Hospital of Oakland Research Institute SSRP / UCSF Benioff (Hepatology)
Clinical Research Assistant | June 2020 - September 2020
More Info

Aghi Lab - UCSF (Neuro-Oncology)
Research Assistant | January 2020 - March 2020 (Research interrupted due to COVID-19 pandemic)
Lab Site

Chapman Lab - UCSF (Pulmonary Immunology)
Research Assistant | May 2019 - September 2019
Lab Site

Sucov Lab - USC (Cardiovascular Regenerative Medicine)
Research Assistant | July 2017 - August 2017
Lab Site (now at MUSC)

Medical Scribe and Data Labeler - DeepScribe
Gastroenterology, Pain Management, Chiropractics, Geriatrics, Psychiatry, Neurology, Orthopedics, Internal Medicine, and Cardiology
August 2019 - May 2021 (300 hours)
More Info